Table 2

Treatment outcomes of metastatic UM on combination ipilimumab and nivolumab

Total cycles of ipilimumab +nivolumab
 114 (16%)
 220 (22%)
 318 (20%)
 437 (42%)
 Median3
Reason for ipilimumab +nivolumab discontinuation
 Progression18 (35%)
 Toxicity29 (57%)
 NA4 (8%)
Maintenance therapy
 Ipilimumab1 (1%)
 Nivolumab26 (29%)
 Pembrolizumab2 (2%)
 No maintenance therapy46 (52%)
 NA14 (16%)
Reason maintenance therapy discontinuation
 Progression16 (55%)
 Toxicity5 (17%)
 Still on nivolumab2 (7%)
 Unknown status6 (21%)
Number of doses of nivolumab monotherapy
 Median7
 Range1–29
 NA4
  • NA, not applicable; UM, uveal melanoma.