Table 2

Immune subsets assessed by multiplex IHC

Marker expressionPanelCell subsetAbbreviation
CD3+CD4+CD8- T cellT-helperT-helper
CD3+CD8+CD4- T cellCD8+ T cellsCD8+ T cells
CD3+CD4+FOXP3+ T cellRegulatory T cellTreg
CD3+CD4-CD8- T cellDouble negative T cellDNT
CD3+ Pan immunePan T cellT cell
CD20+ Pan immuneB cellB cell
CD68+ Pan immuneMacrophageφ
CD68+CD11c+ Pan immuneDendritic cellDC
CD68+PDL1+ Pan immunePDL1+ macrophageφPDL1+
CD68+CD11c+PDL1+ Pan immunePDL1+ dendritic cellDC PDL1+
HMWCK+PDL1+ Pan immunePDL1+ basal cellsHMWCK+PDL1+
HMWCK-PDL1+ Pan immunePDL1+ nonbasal cellsHMWCK-PDL1+
  • IHC, immunohistochemistry.