Table 1

Patient characteristics

Median age61
(range: 46–70)
Sex
 Female5
 Male4
Race
 White7
 African–American2
Smoking status
 Current1
 Former7
 Never1
Performance status
 03
 16
Histology
 ES-SCLC*6
 Atypical carcinoid2
 High-grade neuroendocrine carcinoma1
Brain metastases at baseline†2
  • ** 1 refractory ES-SCLC, 4 relapsed ES-SCLC with 1 patient with stable disease after 2 cycles of second-line chemotherapy, 1 with stable disease after first-line chemotherapy

  • †All treated before study entry

  • ES-SCLC, extensive-stage small-cell lung cancer.