Table 3

Factors associated with OS in patients with NSCLC

CharacteristicsHR95% CIP value
Age
 >75 years0.990.40–2.431
 <75 years1 (reference)
Gender
 Female1.420.66–3.050.4
 Male1 (reference)
Brain metastases
 Presence1.480.70–3.110.3
 Absence1 (reference)
Histological type
 Non-squamous cell carcinoma0.830.34–2.050.7
 Squamous cell carcinoma1 (reference)
PDL1 expression
 ≥50%0.800.44–3.550.7
 <50%1 (reference)
Previous chemotherapy
 None2.090.84–5.190.11
 ≥11 (reference)
MTV
 >36.55.372.17–13.3<0.0001
 <36.51 (reference)
TLG
 >2675.052.05–12.50.0001
 <2671 (reference)
SUVmax
 >13.41.310.63–2.750.5
 <13.41 (reference)
SUVpeak
 >9.71.150.55–2.400.7
 <9.71 (reference)
  • Log-rank test results. MTV, TLG.

  • Median values were used for cut-off.

  • MTV, metabolic tumor volume; NSCLC, non-small cell lung cancer; OS, overall survival; PDL1, programmed death receptor ligand 1; SUVmax, maximum standardized uptake value; SUVpeak, peak standardized uptake value ; TLG, total lesion glycolysis.