Table 1

Related adverse events (AEs) with frequencies ≥10%, by patient

AE, n (%)All patients (n=28)Regimen A (n=19)Regimen B (n=9)
Any gradeGrade 3/4Any gradeGrade 3/4Any gradeGrade 3/4
Fatigue15 (54)010 (53)05 (56)0
Diarrhea13 (46)010 (53)03 (33)0
Vomiting13 (46)09 (47)04 (44)0
Nausea13 (46)08 (42)05 (56)0
Anorexia8 (29)05 (26)03 (33)0
Neutropenia8 (29)5 (14)7 (37)5 (26)1 (11)0
AST increase5 (14)1 (4)2 (11)1 (5)3 (33)0
ALT increase4 (11)1 (4)1 (5)1 (5)3 (33)0
Amylase increase4 (11)1 (4)2 (11)02 (22)1 (11)
Dehydration4 (11)04 (21)000
Lipase increase3 (11)1 (4)1 (5)02 (22)1 (11)
Anemia3 (11)1 (4)3 (16)1 (5)00