Table 1

Respiratory parameters for all patients before and after sarilumab administration

PatientDate of start of symptomsDate of hospitalizationInitial PaO2:FiO2 Date(s) of sarilumab administrationPaO2:FiO2 after sarilumab
1March 15, 2020March 25, 202083March 26, 2020
March 27, 2020		135 at d+1
185 at d+3 after second dose
2March 15, 2020March 25, 2020120March 27, 2020296 at d+1
3March 18, 2020March 24, 2020180March 27, 2020290 at d+1
305 on April 4, 2020
4March 15, 2020March 28, 2020192March 30, 2020230 at d+1
330 on April 10, 2020
5March 18, 2020March 25, 2020200March 26, 2020270 at d+1
370 on April 10, 2020
6March 17, 2020March 27, 2020240March 30, 2020320 at d+1
7March 14, 2020March 26, 202090March 27, 2020
March 28, 2020		62 at d+1
8March 15, 2020March 25, 2020178March 30, 2020
March 31, 2020		290 at d+1
9March 18, 2020March 26, 202070March 27, 2020260 after administration
10March 13, 2020March 23, 2020137April 3, 2020290 at d+1
330 on April 27, 2020
11March 12, 2020March 26, 202012027 March 2020178 at d+1
234 at d+4
382 at d+10
12March 18, 2020March 26, 202060March 27, 2020290 after administration
13March 15, 2020March 25, 2020122March 26, 202072 at d+1
14March 21, 2020March 26, 202088March 27, 202092 at d+1
15March 23, 2020March 30, 2020137March 31, 2020290 at d+1

  • FiO2, fractional inspired oxygen; PaO2, arterial oxygen pressure.