Table 2

Univariate Cox proportional hazard analysis

Overall survival
Variable	HR (95% Cl)	P value
Age	1.01 (0.98 to 1.04)	0.51
Stage 4	1.53 (0.65 to 3.58)	0.33
CA-125	1.00 (1.00 to 1.00)	0.036
Debulking
R1	1.00 (0.33 to 2.98)	0.99
R2	2.06 (1.12 to 3.78)	0.019

	P-TME		M-TME
DC-LAMP	0.74 (0.58 to 0.95)	0.018	0.74 (0.60 to 0.92)	0.006
CD8	0.87 (0.75 to 0.99)	0.039	0.90 (0.78 to 1.03)	0.11
CD20	0.35 (0.09 to 1.33)	0.12	0.85 (0.64 to 1.13)	0.26
NKp46	0.83 (0.54 to 1.27)	0.39	0.95 (0.72 to 1.25)	0.70
M2-like TAMs	0.15 (0.01 to 3.20)	0.22	6.74 (1.58 to 28.68)	0.009

CA-125, cancer antigen 125; DC-LAMP, lysosomal-associated membrane protein; M-TME, metastatic tumor microenvironment; NK, natural killer; P-TME, primary tumor microenvironment; TAMs, tumor-associated macrophages .