Characteristics | Overall population |
N=19 | |
No. (%) | |
Sex | |
Male | 10 (53) |
Female | 9 (47) |
Age (years) | |
Median | 58 |
Range | (35–85) |
Mutation BRAF status | |
Non-mutant | 8 (42) |
Mutant | 10 (53) |
Unknown | 1 (5) |
Lactate dehydrogenase | |
Normal* | 10 (53) |
Elevated | 9 (47) |
M staging: extent of metastases | |
M0 | 3 (16) |
M1a | 2 (11) |
M1b | 6 (32) |
M1c | 8 (42) |
Brain metastases | |
No | 19 (100) |
Yes | 0 (0) |
Site of irradiated lesions | |
Lymph nodes | 9 (47) |
Subcutaneous nodules | 10 (53) |
Visceral organs | 0 (0) |
Previous treatments† | |
No prior systemic treatment | 0 (0) |
Ipilimumab | 0 (0) |
Chemotherapy | 7 (37) |
Anti-BRAF | 8 (24) |
Radiotherapy | 1 (5) |
Surgery | 16 (84) |
*The normal range for lactate dehydrogenase is <247 UI/L.
†All patients were naïve to immune checkpoint inhibitors.