Table 1

Patient baseline characteristics

CharacteristicsOverall population
N=19
No. (%)
Sex
Male10 (53)
Female9 (47)
Age (years)
Median58
Range(35–85)
Mutation BRAF status
Non-mutant8 (42)
Mutant10 (53)
Unknown1 (5)
Lactate dehydrogenase
Normal*10 (53)
Elevated9 (47)
M staging: extent of metastases
M03 (16)
M1a2 (11)
M1b6 (32)
M1c8 (42)
Brain metastases
No19 (100)
Yes0 (0)
Site of irradiated lesions
Lymph nodes9 (47)
Subcutaneous nodules10 (53)
Visceral organs0 (0)
Previous treatments†
No prior systemic treatment0 (0)
Ipilimumab0 (0)
Chemotherapy7 (37)
Anti-BRAF8 (24)
Radiotherapy1 (5)
Surgery16 (84)
  • *The normal range for lactate dehydrogenase is <247 UI/L.

  • †All patients were naïve to immune checkpoint inhibitors.