Table 3

Multivariate Cox proportional hazard analysis

VariableOverall survival
HR (95% Cl)P value
M2-like TAMs (M-TME)10.85 (2.28 to 51.44)0.002
DC-LAMP (P-TME)0.32 (0.14 to 0.73)0.006
  • DC-LAMP, lysosomal-associated membrane protein; M-TME, metastatic tumor microenvironment; P-TME, primary tumor microenvironment; TAMs, tumor-associated macrophages.