Table 4

Change in the log-likelihood of the models with added predictive terms

Variables	∆LRχ²	P value
PFS
Proportion of CD38⁺ cells + PD-L1 + density of CD8⁺ T cells vs proportion of CD38⁺ cells	7.86	0.0197*
Density of CD38⁺CD68⁺ macrophages + PD-L1 +density of CD8⁺ T cells vs density of CD38⁺CD68⁺ macrophages	8.82	0.0121*
OS
Proportion of CD38⁺ cells + PD-L1 + density of CD8⁺ T cells vs proportion of CD38⁺ cells	2.24	0.3260
Density of CD38⁺CD68⁺ macrophages + PD-L1 +density of CD8⁺ T cells vs density of CD38⁺CD68⁺ macrophages	1.03	0.5987

*Statistically significant, as determined with a likelihood ratio test.
LR, likelihood ratio; OS, overall survival; PD-L1, programmed death-ligand 1; PFS, progression-free survival.