Table 1

Murine DC and macrophage subsets and surface markers in different tissues

Tissue	DCs	Macrophages	References
Lung	cDC1: MHC-II^hi, CD11c^hi, CD26^hi, CD24⁺, CD103⁺, XCR1⁺ cDC2: MHC-II^hi, CD11c^hi, F4/80^med, CD206^med/lo, CD26^hi, CD24^med/hi, CD11b^hi, CX₃CR1⁺, SIRPα⁺ moDC: MHC-II^med/hi, CD11c^hi, CD26^lo, CD64⁺, CD24^med, CD11b^hi, SIRPα⁺, CCR2^med, Ly6C^hi, CD209a^hi, CX₃CR1med^hi/med, CD88^med/hi inf-cDC2: MHC-II^hi, CD11c^hi, CD26^hi, CD24^med, CD11b^hi, Ly6C^med/lo, CD209a^med/lo pDC: MHC-II^med/lo, CD11c^med/lo, CD24⁺, Ly6C⁺, PDCA-1⁺, Siglec H⁺, B220⁺	Alveolar macrophage: MHC-II^med/lo, CD11c^hi, CD64⁺, F4/80⁺, CD206⁺, Siglec F⁺, SIRPα⁺ Interstitial macrophage: MHC-II⁺, CD11b⁺, CD11c^lo, CD64⁺, F4/80⁺, CD206^med, SIRPα⁺	19–21 67 158
Kidney	cDC1: MHC-II^hi, CD11c^hi, CD26^hi, CD16^med, CD103⁺, XCR1⁺ cDC2: MHC-II^hi, CD11c^hi, CD64^med/lo, F4/80^med, CD26^hi, CD16^hi, CD11b^hi, CX₃CR1⁺, SIRPα⁺ moDC: MHC-II^med, CD11c^lo, CD64^med, F4/80^med, CD16^hi, CD11b^hi, Ly6C^hi pDC: B220⁺ cells not detected	Kidney macrophage 1: MHC-II^hi, CD11c^med, CD64^hi, CX₃CR1⁺, F4/80^hi, CD11b^lo/med Kidney macrophage 2: MHC-II^hi, CD11c^med, CD64^hi, CX₃CR1⁺, F4/80^lo/med, CD11b^hi	19 20 81 159
Pancreas	cDC1: MHC-II⁺, CD11c⁺, CD103⁺, CD24⁺ cDC2: MHC-II⁺, CD11c⁺, CD11b⁺ CD24⁺ moDC: MHC-II⁺, CD11c⁺. CD24^med, Ly6C^med/lo, F4/80⁺ pDC: CD11c⁺, PDCA-1⁺, B220^dim, Siglec H⁺	Islet macrophage: MHC-II⁺, CD11b⁺, CD11c⁺, F4/80⁺, CD64⁺, CD68⁺, LyzM⁺, CX₃CR1⁺ Stroma CD206⁺ macrophage: MHC-II^med, CD11b⁺, CD11c⁺, F4/80⁺, CD64⁺, CD68⁺, LyzM⁺, CX₃CR1^med, CD206⁺, CD301⁺ Stroma CD206^- macrophage: MHCII⁺, CD11b⁺, CD11c⁺, F4/80⁺, CD64⁺, CD68⁺, LyzM⁺, CX₃CR1^med Pancreas TAM: MHC-II⁺, CD11b⁺, Ly6C^lo/med, F4/80⁺	71 134 137 138 141 160 161
Liver	cDC1: MHC-II^hi, CD11c^hi, CD26^hi, CD103⁺, XCR1⁺ cDC2/moDC: MHC-II^hi, CD11c^hi, CD26^hi, CX₃CR1^hi, F4/80^med, CD11b⁺, SIRPα⁺ pDC: MHC-II^med/lo, CD11c⁺, CD317⁺, Ly6C⁺	Kupffer cell: MHC-II⁺, CD64⁺, F4/80^hi, CD26⁺, SIRPα⁺, Ly6C^lo, CD11b⁺ Liver capsular macrophage: MHC-II⁺, CD11c^lo, CD64⁺, F4/80⁺, CD26⁺, SIRPα⁺, CD14⁺, CD11b⁺, CX₃CR1^hi	19 20 149 162
Ovary/ peritoneal cavity	cDC1: MHC-II⁺, CD11c⁺, F4/80^lo, CD64^lo, CD103⁺, CLEC9A⁺ cDC2: MHC-II⁺, CD11c⁺, F4/80^lo, CD64^lo, CD11b⁺ moDC: MHC-II⁺, CD11c⁺, F4/80^med, CD64^med, CD115⁺	Large peritoneal macrophage: MHC-II^lo, F4/80^hi, CD64⁺, CD11b^hi, MerTK⁺ Small peritoneal macrophage: MHC-II⁺, F4/80^lo, CD11b⁺, CD226⁺, RELMa⁺	121 163 164
Breast	cDC1: MHC-II⁺, F4/80^lo, CD24^hi, CD103⁺ cDC2: MHC-II⁺, F4/80^lo, CD24^hi, CD11b⁺	Breast TAM1: MHC-II⁺, F4/80^hi, CD11b^hi Breast TAM2: MHC-II⁺, F4/80^hi, CD11c^hi	15 97

cDC, conventional dendritic cell; moDC, monocyte-derived dendritic cell; pDC, plasmacytoid dendritic cell moDC; TAM, tumor-associated macrophage.