Table 4

Test performance of CT

Sensitivity, %Specificity, %PPV, %NPV, %
Radiology report
All ICI target combinations50.0074.1472.7351.81
 PD-1/PD-L149.0276.4767.5760.00
 CTLA-4; CTLA-4/PD-151.7257.1483.3322.22
Expert review
All ICI target combinations81.2544.8367.0163.41
 PD-1/PD-L180.3945.1059.4269.70
 CTLA-4; CTLA-4/PD-182.7642.8685.7137.50
  • CTLA-4, cytotoxic T lymphocyte antigen-4; ICI, immune checkpoint inhibitor; NPV, negative predictive value; PD-1/PD-L1, programmed cell death protein 1/programmed cell death protein ligand 1; PPV, positive predictive value.