Most common treatment-related adverse events in oncolytic virus clinical trials
Adverse event | Low grade (1–2) | High grade (3–4) | Total |
Fever | 56 | 4 | 60 |
Chills/rigors | 40 | 0 | 40 |
Nausea/vomiting | 30 | 8 | 38 |
Flu-like symptoms | 27 | 2 | 29 |
Fatigue | 36 | 4 | 40 |
Injection site pain | 15 | 0 | 15 |
Other pain | 19 | 7 | 26 |
*Number of studies reporting the listed event