Table 1

Patient characteristics

CharacteristicsEntire cohort (n=88)Survey respondents (n=63)
Female, n (%)52 (59)37 (59)
Age, mean (SD) years64.3 (11.8)63.4 (11.5)
Caucasian, n (%)75 (85)56 (89)
BMI, mean (SD)28.3 (8.4)28.4 (8.8)
Hypertension, n (%)34 (39)23 (37)
Diabetes, n (%)9 (10)7 (11)
Pulmonary disorder, n (%)8 (9)4 (6.3)
Cancer type, n (%)
 Melanoma24 (27)17 (27)
 Renal19 (22)14 (22)
 Urothelial10 (11)10 (16)
 NSCLC15 (17)8 (13)
 Other17 (19)14 (22)
Active ICI treatment*
 Yes45 (51)25 (40)
 No40 (45)38 (60)
 Unknown3 (3)0 (0)
Months since last follow-up, med (IQR)5 (2,9)3 (1,8)
ICI regimen, n (%)
 Monotherapy PD-1/PD-L162 (70)44 (70)
 Combination26 (30)19 (30)
Cancer response, n (%)
 CR/PR/stable67 (82)49 (78)
 Progression15 (18)10 (22)
Rheumatologic irAE, n (%)
 Small joint arthritis32 (36)22 (35)
 Activated OA15 (17)9 (14)
 PMR8 (9)7 (11)
 Large joint arthritis8 (9)6 (10)
 Arthralgia9 (10)6 (10)
 Sicca syndrome3 (3)3 (5)
 Myositis2 (2)2 (3)
 Other†11 (13)8 (13)
Arthritis medications‡, n (%)
 No medications25 (28)19 (30)
 NSAIDs13 (15)9 (14)
 Steroids39 (44)26 (41)
 HCQ11 (15)6 (10)
 MTX5 (6)4 (6)
 Anti-TNF5 (6)5 (6)
 Tocilizumab3 (3)3 (5)
Arthritis medications changed due to the pandemic--0 (0)
  • *Active ICI treatment=received a dose of ICI within the 6 months preceding the survey.

  • †Other diagnoses include eosinophilic fasciitis, gout, enthesitis, costochondritis, bursitis.

  • ‡Totals do not add up to 100% given that patients can be on multiple medications at a given time.

  • BMI, body mass index; CR, complete response; HCQ, hydroxychloroquine; ICI, immune checkpoint inhibitor; irAE, immune-related adverse effect; MTX, methotrexate; NSAIDs, non-steroidal anti-inflammatory drugs; NSCLC, non-small cell lung cancer; OA, osteoarthritis; PMR, polymyalgia rheumatica; PR, partial response; TNF, tumor necrosis factor.