Table 4

Cox regression analysis

Variables	Univariate			Multivariate*			Multivariate†
Variables	HR	95% CI	P value	HR	95% CI	P value	HR	95% CI	P value
Gender (female vs male)	1.676	0.757–3.707	0.203
Age (<70 vs ≥70)	1.770	0.997–3.143	0.051
Smoking status (non-smoker vs smoker)	1.693	0.990–2.896	0.054
Metastasis (negative vs positive)	0.877	0.214–3.605	0.856
SCLC staging (I–II vs III)	2.111	1.243–3.586	0.006	1.951	1.146–3.322	0.014	1.836	1.077–3.131	0.026
Gal-9 on tumor cells (negative vs positive)	1.108	0.636–1.932	0.717
Gal-9 on TILs (negative vs positive)	0.399	0.195–0.818	0.012	0.436	0.212–0.897	0.024
Risk score (low vs high)	3.874	1.541–9.741	0.004				3.424	1.351–8.676	0.009

Statistically significant data were marked with bold and underline.
*Multivariate Cox regression analysis beyond risk score.
†Multivariate Cox regression analysis that included risk score.
Gal-9, galectin-9; SCLC, small cell lung cancer; TILs, tumor-infiltrating lymphocytes.