Table 2

Response to immunotherapy based on pretreatment BMI trend

OutcomeAny decrease (n=308)No decrease (n=321)P value
Best overall response—no. (%)0.04
 Complete response (CR)31 (10.1)37 (11.5)
 Partial response (PR)54 (17.5)85 (26.5)
 Stable disease (SD)56 (18.2)58 (18.1)
 Progressive disease (PD)162 (52.6)135 (42.1)
 Could not be evaluated5 (1.6)6 (1.9)
Objective response rate*0.01
 No. (%)85 (27.6)122 (38.0)
 95% CI†22.7 to 33.032.7 to 43.6
Disease control rate‡0.01
 No. (%)141 (45.8)180 (56.1)
 95% CI†40.1 to 51.550.1 to 61.6
  • *Objective response rate was defined as the percentage of patients who had CR or PR.

  • †The 95% CIs were calculated using the Clopper-Pearson method.

  • ‡Disease control rate was defined as the percentage of patients who had CR, PR or SD