Table 4

Response to immunotherapy based on baseline PNI

OutcomeLow (n=193)Normal (n=436)P value
Best overall response—no. (%)0.0004
 Complete response (CR)12 (6.2)56 (12.8)
 Partial response (PR)32 (16.6)107 (24.5)
 Stable disease (SD)29 (15.0)85 (19.5)
 Progressive disease (PD)116 (60.1)181 (41.5)
 Could not be evaluated4 (2.1)7 (1.6)
Objective response rate*0.0005
 No. (%)44 (22.8)163 (37.4)
 95% CI†17.1 to 29.432.8 to 42.1
Disease control rate‡<0.0001
 No. (%)73 (37.8)248 (56.9)
 95% CI†31.0 to 45.152.1 to 61.6
  • *Objective response rate was defined as the percentage of patients who had CR or PR.

  • †The 95% CIs were calculated using the Clopper-Pearson method.

  • ‡Disease control rate was defined as the percentage of patients who had CR, PR or SD.