Table 4

Demographic and treatment findings for patients who died

Age	Sex	Country	Cancer type	ICI type	Symptoms	Admitted to hospital	ICU	Reason not to admit to ICU	Primary cause of death	Cytokine release syndrome
80	F	USA	NSCLC	Anti-PD-1/L1	No	Yes	Yes	–	Other	–
73	F	USA	NSCLC	Anti-PD-1/L1	Yes	Yes	Yes	–	COVID-19	No
54	M	USA	Melanoma	Anti-PD-1/L1	Yes	Yes	No	Underlying malignancy	Malignancy	–
51	M	USA	RCC	Anti-PD-1/L1	Yes	Yes	No	Not stated	Malignancy	–
71	F	USA	Urothelial	Anti-PD-1/L1	Yes	No	No	Underlying malignancy	Malignancy	–
61	M	USA	H&NSCC	Anti-PD-1/L1	Yes	Yes	No	Not stated	Other	–
74	M	USA	Gastric	Anti-PD-1/L1	Yes	Yes	No	Not stated	COVID-19	Yes
81	M	USA	Esophageal	Anti-PD-1/L1	Yes	Yes	Yes	–	COVID-19	No
65	M	USA	Esophageal	Anti-PD-1/L1	Yes	Yes	No	Not stated	COVID-19	Yes
45	F	USA	HCC	Anti-PD-1/L1	Yes	Yes	No	Not stated	Malignancy	–
49	F	USA	Sarcoma	Anti-PD-1 plus anti-CTLA-4	No	Yes	Yes	–	COVID-19	Yes
60	M	Canada	NSCLC	Anti-PD-1/L1	Yes	No	No	Not stated	Malignancy	–
56	M	Canada	RCC	Anti-PD-1 plus anti-CTLA-4	Yes	Yes	No	Underlying malignancy	Malignancy	–
65	M	Italy	NSCLC	Anti-PD-1/L1	Yes	Yes	No	Constrained healthcare system	COVID-19	No
73	F	Italy	Melanoma	Anti-PD-1/L1	Yes	Yes	No	Underlying malignancy	COVID-19	No
72	M	Italy	Melanoma	Anti-PD-1/L1	Yes	Yes	No	Constrained healthcare system	COVID-19	No
35	F	UK	Melanoma	Anti-PD-1 plus anti-CTLA-4	No	Yes	No	Underlying malignancy	Malignancy	–
42	M	France	Melanoma	Anti-PD-1 plus anti-CTLA-4	Yes	Yes	No	Underlying malignancy	Malignancy	–

CTLA-4, cytotoxic T-lymphocyte-associated protein 4; F, female; HCC, hepatocellular carcinoma; H&NSCC, head and neck squamous cell carcinoma; ICI, immune checkpoint inhibition; ICU, intensive care unit; M, male; NSCLC, non-small cell lung cancer; PD-1, programmed cell death protein 1; PD-L1, programmed cell death-ligand 1; RCC, renal cell carcinoma.