Table 1

T cell responses to 6 melanoma helper peptides (6MHP)

Arm	Durable T-cell response (dRsp) to 6MHP in PBMC*		Any 2 or more T cell responses (Any2Rsp) to 6MHP in PBMC†		# PBMC samples≥5×	Sentinel immunized node (SIN) responses	# PBMC or SIN samples≥5×
Arm	#/n (%)	(90% CI)	#/n (%)	(90% CI)	Min, max (median)	#/n (%)	(min,max)	Median
A	0/3 (0)	(0 to 63)	0/3 (0)	(0 to 63)	0, 1 (1)	0/3 (0)	0, 1	1
B	2/7 (29)	(5 to 66)	2/7 (29)	(5 to 66)	0, 3 (1)	2/6 (33)	0, 4	1
C	4/6 (67)	(27 to 94)	4/6 (67)	(27 to 94)	0, 4 (2.5)	4/5 (80)	0, 5	3.5
D	15/32 (47)	(32 to 63)	17/32 (53)‡	(37 to 68)	0, 8 (2)	9/29 (31)	0, 8	2

*Durable T cell response (dRsp) to 6MHP defined as T cell responses in PBMC at two or more sequential time points.
†Any2Resp is defined as at least two timepoints with a T cell response to 6MHP, not necessarily sequential.
‡VMM1256 (arm D) had responses at weeks 2, 26, 32, VMM1270 (arm D) had responses at weeks 2, 5, and 11.