Progression pattern | |
Categorical metrics | Number (%) |
Resistance type | |
Primary resistance | 123 (74) |
Secondary resistance | 43 (26) |
Number of involved organ(s) | |
1 | 80 (48) |
2 | 50 (30) |
>=3 | 36 (22) |
General progression pattern | |
Enlargement only | 41 (25) |
New lesion(s) only | 42 (25) |
Both | 83 (50) |
LDH at PD | |
Normal | 72 (43) |
Elevated | 79 (48) |
NA | 15 (9) |
Continuous metrics | Median (range) |
Target lesion size at PD (mm)* | 49.0 (0 to 415.0) |
Tumor enlargement dynamics† | |
Percent change from last evaluation (%) | 26.2 (−100.0 to 241.0) |
Percent change from last evaluation (%) per month | 10.0 (−28.6 to 109.1) |
LDH elevation dynamics‡ | |
Percent change from last evaluation (%) | 6.2 (−33.7 to 354.6) |
Percent change from last evaluation (%) per month | 7.9 (−49.7 to 409.2) |
*Thirteen patients with no available target lesion size data at PD.
†Eighteen patients with no available tumor enlargement dynamics data.
‡Twenty-four patients without LDH dynamics data at PD.
LDH, lactate dehydrogenase; NA, not available; PD, disease progression.