AEs were similar across treatment groups
| Placebo n=11 n (%) | Rapamycin (0.5 mg) n=12 n (%) | Rapamycin (2.0 mg) n=8 n (%) | P value | |
| Any AEs | 6 (55%) | 8 (67%) | 7 (88%) | 0.31 |
| Grade 1 (Mild) | 4 (36%) | 7 (58%) | 5 (63%) | 0.44 |
| Grade 2 (Moderate) | 2 (18%) | 1 (8%) | 2 (25%) | 0.59 |
| Grade 3 (Severe) | 1 (9%)* | 0 | 0 | N/A |
*Severe AE requiring hospitalization but not related to the study drug. Number of patients and percentage of each group experiencing any AE, as well as the most severe AE experienced by each patient (if any). P, χ² test, significance 5%.
AE, adverse event.