Univariate and multivariate analyses for overall survival
| Univariate | Multivariate | |||
| HR (95% CI) | P value | HR (95% CI) | P value* | |
| Genotype | ||||
| AB | 1 | |||
| AA | 2.08 (1.04 to 4.15) | 0.04 | 2.02 (0.97 to 4.2) | 0.06 |
| BB | 1.89 (1 to 3.55) | 0.05 | 1.58 (0.79 to 3.11) | 0.19 |
| Genotype | ||||
| AB | 1 | |||
| AA or BB | 1.96 (1.13 to 3.41) | 0.017 | 1.74 (0.97 to 3.15) | 0.06 |
| Centromere–telomere genotype | ||||
| cA/tB or cB/tA | 1 | 1 | ||
| cA/tA or cB/tB | 2.20 (1.23 to 3.93) | 0.007 | 1.93 (1.02 to 3.65) | 0.044 |
| Centromere genotype | ||||
| Bx/cenA | 1 | |||
| AA | 2.31 (0.99 to 5.37) | 0.05 | 1.67 (0.61 to 4.56) | 0.31 |
*Multivariate analysis includes age, gender and number of metastases as covariates for overall survival; p≤0.05 denotes statistical differences.
Bx, X can be A or B haplotype; cA, centromeric motif A haplotype; cB, centromeric motif B haplotype; p-values in bold, indicates those that are lower than 0.05; tA, telomeric motif A haplotype; tB, telomeric motif of B haplotype.