Correlation between TILs and | Stroma | Tumor | ||
Baseline* | Change† | Baseline* | Change† | |
CD4 | 0.257 | 0.464 | 0.087 | 0.324 |
CD8 | 0.264 | 0.39 | 0.226 | 0.374 |
CD4/CD8 | −0.06 | 0.003 | −0.096 | 0.024 |
T cell | 0.314 | 0.522 | 0.204 | 0.404 |
CD73 | 0.09 | 0.277 | −0.194 | −0.126 |
PD1 in CD4 | −0.068 | 0.035 | 0.07 | 0.161 |
PD1 in CD8 | 0.066 | 0.193 | 0.177 | 0.291 |
PDL1 | 0.47 | 0.27 | 0.447 | 0.124 |
*Correlation between TILs and immune marker levels measured at baseline.
†Correlation between change in TIL levels and change in immune marker levels (changes between baseline and week 3 assessments).
TIL, tumor-infiltrating lymphocyte.