Table 3

PSMA antigen density and EC50 of TNB-585 binding on prostate tumor cell lines

Cell lineAntigen densityEC50 (nM)
22Rv133,000±6024.1
LNCaP170,000±700038.4
MDA-PCa-2b200,000±20028
PC3-PSMA951,000±13 40026.8