Table 3

Univariate and multivariate analyses for progression-free survival

VariablesUnivariate analysisMultivariate analysis
HR (95% CI)P valueHR (95% CI)P value
Baseline fibrinogen
(≥5 ng/mL vs <5 ng/mL)		2.2 (1.3 to 3.5)0.0011.32 (0.8 to 2.2)0.29
On-treatment fibrinogen
(≥4 ng/mL vs <4 ng/mL)		2.71 (1.7 to 4.3)<0.00012.8 (1.3 to 6.03)0.008*
On-treatment NLR
(≥4 vs <4)		2.9 (1.7 to 5)0.00012.2 (1.2 to 4.2)0.015*

  • **P value < 0.05

  • NLR, neutrophil-to-lymphocyte ratio.