Immune-related adverse events by MMR cohort
dMMR | pMMR | |||
Any grade | Grade 3 or higher | Any grade | Grade 3 or higher | |
Eligible patients who received at least one dose of study treatment | 35 | 34 | ||
Patients who experienced at least one immune-related event, n (%) | 7 (20) | 7 (21) | 1 (3) | |
Immune-related events, n (%) | ||||
Hyperthyroidism | 5 (14) | 2 (6) | ||
Hypothyroidism | 3 (9) | 3 (9) | ||
Pneumonitis | 1 (3) | 1 (3) | ||
Adrenal insufficiency | 1 (3) | 0 | ||
Viral hepatitis | 0 | 1 (3) | 1 (3) |
dMMR, mismatch repair deficient; MMR, mismatch mutation repair; pMMR, mismatch repair proficient.