Total (n=1081) | Prevalence by mutation type (%) | Type of CD274 mutations |
Simple mutations | ||
906 | 83.8 | Missense mutations |
97 | 9.0 | Truncations |
24 | 2.2 | Splice site mutations |
9 | 0.8 | Insertion/deletions |
Complex mutations | ||
21 | 1.9 | Two missense mutations |
13 | 1.2 | Missense mutation with amplification |
6 | 0.6 | Missense mutation with truncation |
1 | 0.1 | S149Y, CD274–PLGRKT |
1 | 0.1 | R140T, E187Q, deletion, CD274–CD274 |
1 | 0.1 | L106*, amplification (copy number 90), CD274–CD274 |
1 | 0.1 | P235S, S279L, amplification (copy number 12) |
1 | 0.1 | R86Q, G95E, W57*, splice site 682+1G>A |