Table 2
Total (n=1081)Prevalence by mutation type (%)Type of CD274 mutations
Simple mutations
90683.8Missense mutations
979.0Truncations
242.2Splice site mutations
90.8Insertion/deletions
Complex mutations
211.9Two missense mutations
131.2Missense mutation with amplification
60.6Missense mutation with truncation
10.1S149Y, CD274–PLGRKT
10.1R140T, E187Q, deletion, CD274–CD274
10.1L106*, amplification (copy number 90), CD274–CD274
10.1P235S, S279L, amplification (copy number 12)
10.1R86Q, G95E, W57*, splice site 682+1G>A