IBD cohort incidence of imDC, colitis, and diarrhea
| N (%) | Incidence of imDC | % | |
| Total IBD cohort | 30 (100) | 11 | 37 |
| Gender | |||
| Female | 18 (60) | 8 | 44 |
| Male | 12 (40) | 3 | 25 |
| IBD type | |||
| CD | 19 (63) | 6 | 32 |
| UC | 10 (33) | 5 | 50 |
| IBD-U | 1 (3) | 0 | 0 |
| History of other autoimmune diseases | |||
| Yes | 7 (23) | 5 | 71 |
| No | 23 (77) | 6 | 26 |
| History of extra-intestinal manifestations | |||
| Yes | 6 (20) | 3 | 50 |
| No | 24 (80) | 8 | 33 |
| Smoking status | |||
| Smoker | 5 (17) | 2 | 40 |
| Ex-smoker | 16 (53) | 5 | 31 |
| Never smoker | 9 (30) | 4 | 44 |
| Small bowel surgery | |||
| Yes | 9 (30) | 4 | 44 |
| No | 21 (70) | 7 | 33 |
| Large bowel surgery | |||
| Yes | 14 (47) | 4 | 29 |
| No | 16 (53) | 7 | 44 |
| Any bowel surgery | |||
| Yes | 15 (50) | 4 | 27 |
| No | 15 (50) | 7 | 47 |
| IBD medications held due to cancer diagnosis | |||
| Yes | 9 (30) | 5 | 56 |
| No | 21 (70) | 6 | 29 |
| Active disease at ICI start | |||
| Yes | 3 (10) | 1 | 33 |
| No | 27 (90) | 10 | 37 |
| IBD treatment at ICI start | |||
| Yes | 10 (33) | 3 | 30 |
| No | 20 (67) | 8 | 40 |
CD, Crohn’s disease; IBD-U, inflammatory bowel disease—undeterminate; ICI, immune checkpoint inhibitor; imDC, immune-mediated diarrhea and colitis; UC, ulcerative colitis.