Table 3

Frequency of DM-sensitive T-cell reactivity among CD4+ T-cell libraries generated from naïve (TN), central memory (TCM), effector memory (TEM) and effector memory RA (TEMRA) T-cells

Epstein-Barr virusCytomegalovirusP value
TN31% (56/183)6% (6/100)<0.001
TCM36% (75/210)6% (9/162)<0.001
TEM27% (74/274)0% (0/102)<0.001
TEMRA26% (66/251)6% (7/122)<0.001
  • Depicted are percentages and absolute numbers of T-cell lines with DM-sensitive properties in relation to all reactive T-cell lines. Significance was calculated using Pearson’s χ2 test or Fisher’s exact test for small numbers (TEM).