Table 3

OS and EFS of high-risk neuroblastoma patients according to T cell inflammation group and other established prognostic markers

CharacteristicComparisonOverall survivalEvent-free survival
HR95 CI low95 CI highP-valueHR95 CI low95 CI highP-value
T cell inflammation groupT cell-inflamed vs non-T cell-inflamed0.5580.3170.9820.043*0.6910.4081.1710.170
Intermediate vs non-T cell-inflamed0.4210.2180.8150.010*0.6350.3531.1430.130
MYCN statusAmplified vs
not amplified
PloidyHyperdiploid vs
Age (months)Continuous variable0.9980.9911.0060.6880.9950.9871.0030.245
  • HR and p-values were calculated using Cox proportional hazards models.

  • *p<0.05, **p<0.01, ***p<0.001.

  • CI, confidence interval; EFS, event-free survival; HR, hazard ratio; OS, overall survival.