Table 3

OS and EFS of high-risk neuroblastoma patients according to T cell inflammation group and other established prognostic markers

Characteristic	Comparison	Overall survival				Event-free survival
Characteristic	Comparison	HR	95 CI low	95 CI high	P-value	HR	95 CI low	95 CI high	P-value
T cell inflammation group	T cell-inflamed vs non-T cell-inflamed	0.558	0.317	0.982	0.043*	0.691	0.408	1.171	0.170
T cell inflammation group	Intermediate vs non-T cell-inflamed	0.421	0.218	0.815	0.010*	0.635	0.353	1.143	0.130
MYCN status	Amplified vs not amplified	1.281	0.734	2.236	0.384	1.155	0.694	1.923	0.580
Ploidy	Hyperdiploid vs diploid	0.606	0.366	1.001	0.050	0.682	0.434	1.071	0.097
Age (months)	Continuous variable	0.998	0.991	1.006	0.688	0.995	0.987	1.003	0.245

HR and p-values were calculated using Cox proportional hazards models.
*p<0.05, **p<0.01, ***p<0.001.
CI, confidence interval; EFS, event-free survival; HR, hazard ratio; OS, overall survival.