Percentage of inhibition of tumor cell killing for each concentration of dasatinib was calculated over that in the absence of dasatinib for a fixed HLA-A2 WT1-TCB concentration of 10 nM in the assay of figure 1A, mean of n=2 donors
Dasatinib (ng/mL) | Dasatinib (nM) | Inhibition (%) |
48.80 | 100.00 | 94.20 |
24.40 | 50.00 | 95.90 |
12.20 | 25.00 | 87.90 |
6.10 | 12.50 | 80.10 |
3.05 | 6.25 | 33.00 |
0.00 | 0.00 | 0.00 |