Table 1

Recorded clinical trials of chimeric non-antigen receptors in ClinicalTrials.gov

Receptors	NCT#	Phase	Status	Condition or disease	Intervention/treatment	Sponsor	First posted	Refs
PD1-CD28	NCT02930967	1	Unknown	PD-L1 +malignant tumors	Autologous CSR T	China Meitan General Hospital, China	October 12, 2016	n/a
	NCT02937844	1	Unknown	Glioblastoma multiforme	Anti-PD-L1 CSR T cells Cyclophosphamide fludarabine	Beijing Sanbo Brain Hospital, China	October 19, 2016	n/a
	NCT03258047	2	Unknown	B cell lymphoma	CAR-T	First Affiliated Hospital of Zhejiang University, China	August 22, 2016	33 34
CD200R-9aas-CD28cys	NCT01640301	2	Active, not recruiting	Acute myeloid leukemia HLA-A*0201 Positive	WT1-sensitized allogeneic T-lymphocytes	Fred Hutchinson Cancer Research Center, USA	July 13, 2012	39
NKG2D-based	NCT04658004	1	Not yet recruiting	Acute myeloid leukemia	NKG2D CAR T-cells	Zhejiang University, China	December 08, 2020	n/a
	NCT03415100	1	Recruiting	Solid tumors	CAR-NK cells targeting NKG2D ligands	The Third Affiliated Hospital of Guangzhou Medical University, China	January 30, 2018	n/a
	NCT04550663	1	Not yet recruiting	Hepatocellular carcinoma Colorectal cancer Glioma	KD-025 CAR-T cells	The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, China	September 16, 2020	n/a
	NCT04717999	n/a	Not yet recruiting	Recurrent glioblastoma	NKG2D CAR-T	UWELL Biopharma, Taiwan	January 22, 2021	n/a
	NCT02203825	1	Completed	Acute myeloid leukemia myelodysplastic syndrome multiple myeloma	CM-CS1 T-cell infusion	Celyad Oncology SA, Belgium	July 30, 2014	66