Table 2

Univariate Cox regression analysis for recurrence-free survival

Variables	HR	95% CI	P value
HLA class II on TILs (negative vs positive)	0.507	0.288 to 0.893	0.019*
HLA class II on tumor cells (negative vs positive)	1.964	0.885 to 4.355	0.097
PD-1 on TILs (negative vs positive)28	0.602	0.342 to 1.059	0.078
PD-L1 on TILs (negative vs positive)28	0.417	0.223 to 0.779	0.006*
PD-L1 on tumor cells (negative vs positive)	0.815	0.198 to 3.347	0.776
FOXP3 (negative vs positive)28	0.376	0.194 to 0.730	0.004*
CD3 (negative vs positive)28	0.480	0.281 to 0.820	0.007*
CD4 (negative vs positive)28	0.450	0.245 to 0.825	0.010*
CD8 (negative vs positive)28	0.400	0.206 to 0.776	0.007*

*P<0.05 indicates statistical significance.
HLA class II, human leukocyte antigen class II; PD-1, programmed death-1; PD-L1, programmed death-ligand 1; TILs, tumor infiltrating lymphocytes.