Association of specific mutations and pneumonitis development using statistical Fisher’s exact values
| Gene | Non-pneumonitis (n=24) | Pneumonitis (n=5) | Total (n=29) | P value |
| KEAP1—n (%) | 0.127 | |||
| Wt | 22 (88) | 3 (12) | 25 | |
| Mut | 2 (50) | 2 (50) | 4 | |
| ARID1A—n (%) | 0.068 | |||
| Wt | 23 (88.5) | 3 (11.5) | 26 | |
| Mut | 1 (33.3) | 2 (66.7) | 3 | |
| RB1—n (%) | 1 | |||
| Wt | 21 (80.8) | 5 (19.2) | 26 | |
| Mut | 3 (100) | 0 (0) | 3 | |
| HNF1A—n (%) | 1 | |||
| Wt | 19 (82.6) | 4 (17.4) | 23 | |
| Mut | 5 (83.3) | 1 (16.7) | 6 | |
| TP53—n (%) | 0.622 | |||
| Wt | 15 (88.2) | 2 (11.8) | 17 | |
| Mut | 9 (75) | 3 (25) | 12 | |
| KRAS—n (%) | 0.553 | |||
| Wt | 21 (84) | 4 (16) | 25 | |
| Mut | 3 (75) | 1 (25) | 4 |
Mut, mutated; Wt, wild-type.