Table 1
Disease categoryCountPercentICD codesMedDRA codes*
Atrial fibrillation14334I48.x10003658
Heart failure9523I50.x
Exclude I50.2(2-4)x
10019279
Pericardial disease8420I3(0–1).x
Exclude I31.3x
10034474, 10034484, 10053565
Unspecified arrhythmia399I49, I49.(89)x
Cardiac arrest205I46.x10007515
Premature depolarization205I49.(1–4)x
Atrioventricular block133I44.x10003673
Sick sinus syndrome31I149.5x
Myocarditis10I4(0–1).x
Exclude I40.0x
Ventricular arrhythmia00I49.0x
Total418100
  • Table 1. Distribution of cardiac events among patients receiving PD-1/PD-L1 therapy. PD-1, Programmed cell death protein 1; PD-L1, Programmed death-ligand 1.

  • *Only MedDRA codes present in the ConcertAI database are listed. This is not an exhaustive list.

  • ICD, International Classification of Diseases; MeDRA, Medical Dictionary for Regulatory Activities.