Comparison of next-generation sequencing-defined MSI-high group with the clinical MMR phenotype
| Clinical phenotype | Total (%) | |||
| MMR-deficient (%) | MMR-proficient (%) | |||
| NGS phenotype | MSI-high | 15 (79) | 0 | 15 (36) |
| MSS | 4 (21) | 23 (100) | 27 (64) | |
| Total | 19 (100) | 23 (100) | 42 (100) | |
Fisher’s exact test p<0.0001.
MMR, mismatch repair; MSI, microsatellite instability; MSS, microsatellite stable; NGS, next-generation sequencing.