Table 2

Comparison of next-generation sequencing-defined MSI-high group with the clinical MMR phenotype

Clinical phenotypeTotal (%)
MMR-deficient (%)MMR-proficient (%)
NGS phenotypeMSI-high15 (79)015 (36)
MSS4 (21)23 (100)27 (64)
Total19 (100)23 (100)42 (100)
  • Fisher’s exact test p<0.0001.

  • MMR, mismatch repair; MSI, microsatellite instability; MSS, microsatellite stable; NGS, next-generation sequencing.