Table 1

Summary of the clinical features of the enrolled cases (N=67)

Parameters*MSI-high (N=20) (%)POLE-mutated (N=47) (%)Total (%)
Age (mean±SD)48.8±11.961.4±11.757.7±13.1
SexMale14 (70)30 (64)44 (66)
Female6 (30)17 (36)23 (34)
Type of malignanciesCRC14 (70)25 (53)39 (58)
NSCLC012 (26)12 (18)
GC3 (15)6 (13)9 (13.5)
GBM2 (10)02 (3)
OV1 (5)1 (2)2 (3)
BC01 (2)1 (1.5)
SCLC01 (2)1 (1.5)
HNSCC01 (2)1 (1.5)
  • *Defined by the published criteria of Kim et al.19

  • BC, breast cancer; CRC, colorectal cancer; GBM, glioblastoma; GC, gastric cancer; HNSCC, head and neck squamous cell carcinoma; MSI, microsatellite instability; NSCLC, non-small cell carcinoma; OV, ovarian cancer; SCLC, small cell lung carcinoma.