Table 1

Univariate and multivariate Cox proportional hazard models for RFS

VariableUnivariateMultivariate
HR (95% CI)p-valueHR (95% CI)p-value
Age, years0.997 (0.971 to 1.024)0.837Not Included
Positive lymph node, number1.089 (1.049 to 1.131)<0.0011.093 (1.048 to 1.140)<0.001
Tumor size, cm1.462 (1.117 to 1.816)0.0011.368 (1.085 to 1.724)0.008
HRD score0.997 (0.989 to 1.006)0.525Not Included
PAM50
 BasalRefNot Included
 Others1.375 (0.749 to 2.524)0.304
Tumor HLA-I LOH
 LOHRefRef
 Non-LOH0.459 (0.245 to 0.860)0.0150.307 (0.158 to 0.596)<0.001
TNBC immune subtype
 Immune-inflamedRefRef
 Non-immune-inflamed2.519 (1.067 to 5.946)0.0352.784 (1.169 to 6.629)0.033
  • HRs and p-values of the covariates in the univariate and multivariate Cox proportional hazard models for RFS.

  • CI, confidence interval; HLA, human leukocyte antigen; HRD, homologous recombination deficiency; LOH, loss of heterozygosity; RFS, relapse-free survival; TNBCs, triple-negative breast cancers.