Characteristic | No of patients (%, N=76) |
Age, median (range) | 67 (25–92) |
Male sex | 50 (66) |
Cancer type | |
Melanoma | 62 (82) |
Lung | 5 (7) |
Head and neck cancer | 2 (3) |
Esophageal adenocarcinoma | 2 (3) |
Other | 5 (7) |
Cancer stage | |
III | 21 (28) |
Adjuvant/neoadjuvant | 9 (12) |
Non-adjuvant | 12 (16) |
IV | 55 (72) |
Adjuvant | 1 (1) |
Non-adjuvant | 54 (71) |
Immunotherapy class | |
Anti-PD-1/PD-L1 | 51 (67) |
Anti-CTLA-4 | 8 (11) |
Combination PD-1/CTLA-4 blockade | 17 (22) |
Type of psoriasis | |
Plaque | 46 (61) |
Guttate* | 4 (5) |
Pustular | 2 (3) |
Psoriatic arthritis only | 3 (4) |
Not specified/unknown | 21 (28) |
Psoriatic arthritis | 15 (20) |
Median duration of psoriasis symptoms, years (range) | 9 (1 month–54 years) |
Other extracutaneous disease associations (including uveitis/iritis, IBD, CVD) | 10 (13) |
Prior psoriasis therapy | |
Acitretin | 1 (1) |
Biologics† | 3 (4) |
Methotrexate‡ | 6 (8) |
Prednisone | 1 (1) |
Small molecule inhibitors | 3 (4) |
Topical therapy only | 27 (36) |
None | 35 (46) |
Active immunosuppressant psoriasis therapy at start of immunotherapy | 2 (3) |
Other pre-existing autoimmune disease | 6 (8) |
Biologics include adalimumab and etanercept. Small molecule inhibitors include tofacitinib and apremilast.
*Includes two patients with guttate and plaque psoriasis.
†One patient on acitretin.
‡One patient on prednisone.
CVD, cardiovascular disease; IBD, inflammatory bowel disease.