Imaging and biological characteristics of the patients
| Patient ID | 68Ga-DOTATOC PET/CT | CMR imaging | hs troponine I values (n >25 ng/L) | Other investigations | Classification bonaca et al | ||
| Uptake pattern | Highest ratio SUVpeak_M/SUVmean_IC * | Days from symptom onset and PET/CT | |||||
| Patient 1 | ND | ND | ND | Intramyocardial lesions, edema and pericarditis | ND | TTE =no alteration of LV function/ECG=no kinetic alterations/hs troponin T=229 ng/L (n <14 ng/L)/creatinin kinase=140 CK U/L (N 25–190) U/L | Definite |
| Patient 2 | ND | ND | ND | Minimal subepicardial lesions, no edema | 18.8 | TTE=no alteration of LV function/ECG=no kinetic alteration/troponin T=387 ng/L/CK=178 U/L | Definite |
| Patient 3 | Heterogenous | 2.2 | 7 | Absence of edema or intramyocardial scars of inflammatory type | 88.7 | TTE=ND/ECG=AVB I and LAHB/troponin T=1231 ng/L/CK=6249 U/L | Possible |
| Patient 4 | Patchy diffuse | 2.3 | 3 | ND | 981.9 | TTE=no alteration of LV function/ECG=new AVB/troponin T=1045 ng/L (<14) /CK=2234 U/L (<190) | Possible |
| Patient 5 | Patchy diffuse | 3.1 | 4 | ND | 169.9 | TTE=no alteration of LV function or kinetics/ECG=new intermittent high-grade AVB/troponin T=2389 ng/L/CK=524 U/L | Possible |
| Patient 6 | Patchy diffuse | 4.4 | 10 † | Absence of edema or intramyocardial scars of inflammatory type. | 1604.7 | TTE=no alteration of LV function or kinetics/ECG=diffuse alterations of the repolarization with submillimetre undershift and flattened T wave/troponin T=1281 ng/L/CK=4752 U/L | Possible |
| Patient 7 | Patchy diffuse | 2.9 | 3 | Absence of edema or intramyocardial scars of inflammatory type | 212.6 | TTE=no alteration of LV function or kinetics/ECG=sinusal rythm, no modification/troponin T=936 ng/L/CK=844 U/L | Possible |
| Patient 8 | Patchy diffuse | 3.3 | 5 | Late-gadolinium enhancement (patchy pattern) and edema | 5896.1 | TTE=no alteration of LV function or kinetics/ECG=new bundle branch block/troponin T=966 ng/L/CK=127 U/L | Definite |
| Patient 9 | Heterogenous | 2.4 | 3 | Absence of edema or intramyocardial scars of inflammatory type | 20.5 | TTE=NF/ECG=sinusal rythm/troponin T=1210 ng/L/CK=280 U/L | Possible |
| Patient 10 | Heterogenous | 3.5 | 1 † | Absence of edema or intramyocardial scars of inflammatory type | 28 | TTE=no alteration of LV function or kinetics, minimal pericardial effusion/ECG=sinusal rythm/troponin T=40 ng/L/CK=235 U/L | Possible |
| Patient 11 | Heterogenous | 4.4 | 13 | ND | 110 | TTE=low LV function (18%) and alterations of segmental kinetics/ECG=sinusal rythm/troponin T=150 ng/L/CK=40 U/L | Probable |
Troponin I normal values <26 ng/L; troponin T normal values <14 ng/L; CK normal values <190 ng/L.
*MBRpeak: SUVpeak_M to left ventricular intracavitary background SUVmean ratio.
†Two patients had immunosuppressive treatment initiated on the same day as the PET/CT.
AVB, atrioventricular block; CK, creatine kinase; 68Ga-DOTATOC, 68Ga-DOTA(0)-Phe(1)-Tyr(3)-octreotide; hs, high-sensitivity; LAHB, left anterior hemiblock; LV, left ventricle; MBRpeak, myocardium-to-background ratio of myocardium SUVpeak to LV intracavitary SUVmean; ND, not done; NF, not found; PET, positron emission tomography; SUVpeak_M, myocardial SUVpeak; TTE, transthoracic echocardiogram.