Age | Median (range) | 57.6 (30.1–82.8) |
Gender | Male | 17 |
Female | 9 | |
American Joint Committee on Cancer stage | III | 4 |
M1A | 0 | |
M1B | 3 | |
M1C | 11 | |
M1D | 7 | |
Primary site | Cutaneous | 17 |
Acral | 4 | |
Subungual | 1 | |
Unknown primary | 4 | |
Driver mutation | BRAF | 10 |
NRAS | 5 | |
Other* | 2 | |
No driver identified | 6 | |
Not tested | 3 | |
Tumor mutation burden | High | 11 |
Low | 11 | |
Unknown | 4 | |
First course of ipi/nivo | Median # doses (range) | 4 (1–4) |
# of patients receiving maintenance anti-PD1 | 16 | |
Reinduction course of ipi/nivo | Median # of doses (range) | 3 (1–4) |
Months between courses | Median (range) | 22.2 (6–49.1) |
*One patient had KRAS G12V; the other had two NF1 alterations, X421_splice and Q392* and SF3B1 G740E.
ipi/nivo, ipilimumab/nivolumab.