Univariate and multivariate prognostic analyses for MFS
| Characteristics | Univariate | Multivariate | ||||
| N | HR (95% CI) | P value | N | HR (95% CI) | P value* | |
| Age (years) | 371 | 1.00 (0.99 to 1.01) | 0.902 | |||
| Gender | ||||||
| Male vs female | 371 | 1.02 (0.70 to 1.49) | 0.909 | |||
| Tumor site | ||||||
| Head and neck vs extremity | 382 | 0.00 (0.00 to Inf) | 0.66 | |||
| Internal trunk vs extremity | 0.77 (0.50 to 1.18) | |||||
| Superficial trunk vs extremity | 0.81 (0.47 to 1.40) | |||||
| Depth | ||||||
| Superficial vs deep | 196 | 0.78 (0.38 to 1.61) | 0.495 | |||
| Pathological type | ||||||
| Liposarcoma vs leiomyosarcoma | 678 | 0.48 (0.35 to 0.67) | 1.35E−06 | 678 | 0.58 (0.41 to 0.81) | 1.51E−03 |
| Myxofibrosarcoma vs leiomyosarcoma | 0.45 (0.24 to 0.86) | 678 | 0.52 (0.27 to 0.98) | 4.44E−02 | ||
| Other vs leiomyosarcoma | 0.21 (0.08 to 0.57) | 678 | 0.25 (0.09 to 0.69) | 7.65E−03 | ||
| Undifferentiated sarcoma vs leiomyosarcoma | 0.43 (0.30 to 0.61) | 678 | 0.47 (0.33 to 0.68) | 4.40E−05 | ||
| Pathological tumor size, cm | 210 | 1.00 (0.96 to 1.04) | 0.898 | |||
| Pathological FNCLCC grade | ||||||
| 3 vs 1–2 | 307 | 1.43 (0.95 to 2.17) | 0.088 | |||
| CINSARC risk | ||||||
| High vs low | 678 | 2.48 (1.87 to 3.28) | 2.03E−10 | 678 | 2.19 [1.65 to 2.92) | 8.14E−08 |
| ICR classification | ||||||
| 1 vs 2–3 | 678 | 1.59 (1.20 to 2.08) | 1.11E−03 | 678 | 1.52 (1.15 to 2.00) | 3.54E−03 |
*Wald test.
FNCLCC, Fédération Nationale des Centres de Lutte Contre le Cancer; ICR, immunologic constant of rejection; MFS, metastasis-free survival .