MDNA11 binding to human, cynomolgus or murine IL-2 receptors
| IL-2Rβ (CD122) Binding KD (nM) | IL-2Rα (CD25) Binding KD (nM) | |||||
| Human | Cynomolgus | Mouse | Human | Cynomolgus | Mouse | |
| rhIL-2 | 210±30 | 170±9 | N.D. | 24±1 | 12±2 | 32.4±0.1 |
| MDNA11 | 6.6±0.1 | 8.2±0.1 | 170±9 | No binding | No binding | No binding |
N.D., not determined; rhIL, recombinant human interleukin.