Parameters associated with postoperative disease recurrence and overall mortality of ccRCC patients after adjusting for confounding variables in the univariate and multivariate Cox regression analyses
| Variables | Disease-free survival | Overall survival | ||||
| Univariate | Multivariate | Univariate | Multivariate | |||
| P value | HR (95% CI) | P value | P value | HR (95% CI) | P value | |
| Sex (male vs female) | 0.713 | 0.072 | ||||
| Age at surgery (>60 years vs <60 years) | 0.222 | 0.007 | 2.57 (1.14 to 5.74) | 0.022 | ||
| Pathological T stage (pT3/4 vs pT1/2) | <0.001 | 1.94 (1.08 to 3.46) | 0.026 | <0.001 | ||
| Tumor grade (G3/4 vs G1/2) | <0.001 | 3.00 (1.68 to 5.36) | <0.001 | <0.001 | 4.74 (2.18 to 10.27) | <0.001 |
| Venous invasion (positive vs negative) | 0.056 | 0.190 | ||||
| Tumor size (>60 mm vs <60 mm) | <0.001 | 0.009 | ||||
| TLS (positive vs negative) | <0.001 | 2.57 (1.50 to 4.40) | 0.001 | <0.001 | 3.04 (1.42 to 6.48) | 0.004 |
ccRCC, clear cell renal cell carcinoma; TLS, tertiary lymphoid structure.