Comparison of serum proteomic tests and validation status
| HIC | PIR | PerspectIV | |
| Components in signature (n, type) | 8 spectral features11 | 274 spectral features16 | 8 glycoproteins17 |
| Date first published* or presented** | 2007*11 | 2018**43 | 2019**17 |
| Designed for immunotherapy? | No11 | Yes16 | Yes17 |
| Test locked? | Completed | Completed | Pending |
| Independent cohort validation? | Completed21 | Completed38 | Pending |
| Prospective clinical validation? | Completed20 | Pending | Pending |
HIC, host immune classifier; PIR, primary immune response.