Table 2

Tumor responses

All patients (N=36)Primary tumor type
Bladder cancer (n=18)Other types (n=18)
Best overall response, n (%)
 Complete response1 (2.8)1 (5.6)0
 Partial response10 (27.8)6 (33.3)4 (22.2)
 Stable disease12 (33.3)7 (38.9)5 (27.8)
 Progressive disease10 (27.8)3 (16.7)7 (38.9)
 Not evaluable3 (8.3)1 (5.6)2 (11.1)
Objective response rate, % (95% CI)30.6 (16.3 to 48.1)38.9 (17.3 to 64.3)22.2 (6.4 to 47.6)
Disease control rate, % (95% CI)63.9 (46.2 to 79.2)77.8 (52.4 to 93.6)50.0 (26.0 to 74.0)
Median time to response (range), months2.1 (1.9–2.1)2.1 (2.0–2.1)2.1 (1.9–2.1)
Duration of response
 Patients with ongoing response, n/N (%)5/11 (45.5)4/7 (57.1)1/4 (25.0)
 Median (95% CI)6.3 (2.1 to NR)NR (4.2 to NR)4.2 (2.1 to NR)
 6-month rate72.7% (37.1 to 90.3)85.7% (33.4 to 97.9)50.0% (5.8 to 84.5)
  • NR, not reached.