Demographics and clinical characteristics of all patients
| Characteristics | Escalation | Expansion |
| No of patients | 14 | 20 |
| Age (years), mean (IQR) | 52.3 (47.0–70.3) | 66.1 (56.9–73.5) |
| Sex | ||
| Male | 7 | 10 |
| Female | 7 | 10 |
| ECOG PS at baseline | ||
| 0 | 4 | 6 |
| 1 | 10 | 14 |
| Tumor type | ||
| Non-small cell lung cancer | 3 (21.4) | 11 (55.0) |
| Cervical cancer | 2 (14.3) | 0 (0) |
| Cholangiocarcinoma | 2 (14.3) | 1 (5.0) |
| Colorectal cancer | 1 (7.1) | 0 (0) |
| Breast cancer | 2 (14.3) | 0 (0) |
| Prostate cancer | 0 (0) | 2 (10.0) |
| Ovarian cancer | 1 (7.1) | 1 (0) |
| Mesothelioma | 3 (21.4) | 4 (20.0) |
| Renal cell cancer | 0 (0) | 1 (5.0) |
| Median no of prior lines of therapies and range | 2.5 (1–7) | 3 (1–8) |
ECOG PS, Eastern Co-operative group performance status; IQR, interquartile range.