Table 1

Patients’ characteristics who received NY-ESO-1-TCR-gene transduced lymphocyte transfer

CohortPatient noAge at entry (years)SexHLA-A typeDiseaseNY-ESO-1 expression (IHC %)Tumor lesions at entry
1 (5×108 cell dose)1Late 60sF02:01Breast cancer5–<25Lung, lymph node
2Early 40sF02:01Synovial sarcoma≥75Lung
3Early 70sM02:01Malignant salivary tumor<5Primary lesion at parotid gland
2 (5×109 cell dose)7Late 40sM02:01Synovial sarcoma≥75Soft tissue at femoral area, lung
9Early 60sM02:01Melanoma≥75Skin, liver, peritonium
8Early 70sM02:01Synovial sarcoma≥75Chest wall, soft tissue at inguinal area, bone
14Late 60sF02:06Ovarian cancer25–<50Lymph node
16Late 20sM02:06Synovial sarcoma≥75Lung
15Late 40sF02:01Myxoid liposarcoma50–<75Retroperitonium
  • IHC, immunohistochemistry; TCR, T cell receptor.