Table 1

X-ray data processing and model refinement information

ParameterProtein crystallographic details
Data processing
Protein contentc728 TCRc728 TCR and HLA-A*02:01/MAGEA10-GVY-9c796 TCR and HLA-A*02:01/MAGEA10-GVY-9c756 TCR and HLA-A*02:01/MAGEA10-GVY-9
Space groupP1P1P21P21
Unit cell parameters:
 Lengths a, b, c (Å)54.9, 59.2, 86.054.1, 95.8, 106.354.3, 77.5, 115.154.2, 77.4, 116.7
 Angles α, β, λ (°)101.9, 105.9, 104.7109.2, 96.5, 99.790.00, 102.9, 90.090.0, 102.7, 90.0
Resolution range (Å)79.0–2.2781.9–1.8277.5–2.0477.5–1.54
No. of unique reflections38 348158 06259 081134 415
I/σ(I)4.3 (2.3)4.7 (0.7)5.7 (1.6)6.4 (1.0)
Rmeas16.6 (29.7)13.9 (95.0)14.5 (90.4)10.5 (138.1)
Multiplicity1.5 (1.5)1.5 (1.4)2.9 (2.8)3.2 (3.1)
CC1/20.957 (0.898)0.986 (0.464)0.988 (0.728)0.995 (0.331)
Completeness (%)86.2 (84.5)90.2 (87.5)99.3 (98.7)96.9 (95.8)
Model details and refinement statistics
Rwork (%)19.2 (25.5)20.2 (33.6)18.6 (29.3)20.2 (33.9)
Rfree (%)25.2 (31.9)22.9 (33.4)23.6 (30.9)23.6 (32.1)
No. of atoms706113 73568297098
No. of waters299637349528
No. of copies in asymmetric unit2211
Ramachandran plot (%)
Favored regions96.997.496.397.5
Allowed regions3.12.63.72.4
Outliers0000.1
  • HLA, human leucocyte antigen; TCR, T-cell receptor.