Table 2

Common grade 3 or higher adverse events (≥20%)

Low-dose groupMedium-dose groupHigh-dose groupTotal
N=4N=13N=14(n=31)
Hematologic
Leukopenia4 (100)11 (84.6)14 (100)29 (93.5)
Lymphopenia4 (100)12 (92.3)14 (100)30 (96.8)
Neutropenia4 (100)11 (84.6)13 (92.9)28 (90.3)
Thrombocytopenia4 (100)4 (30.8)4 (28.6)12 (38.7)
Anemia3 (75.0)6 (46.2)6 (42.9)15 (48.4)
Others
Pneumonia0 (0.0)3 (23.1)4 (28.6)7 (22.6)